793 Examining the True Incidence and Staging of Amelanotic Melanoma in an Irish Population

Abstract Introduction Many patients diagnosed with amelanotic melanoma (AM) have often gone undetected for a long time due to the difficulty in diagnosis of these skin lesion, likely causing underestimation prevalence AM Ireland. This study aims determine associated risk factors, incidence, and an Irish population. Aim Determine true staging melanoma. Method is retrospective cohort diagnoses made 2019 two large hospitals. Data was extracted from hospital patient records histopathology reports, based on confirmed melanomas. clinically defined as melanomas devoid pigment visual inspection before biopsy. Results A total 265 were included. The overall 17%. Comparison age between non-AM (pigmented melanoma) showed significantly higher (73 +/- 14 versus 66 15 years). Breslow Thickness (3.4 +/-3.7 1.6 +/-1.8), which indicator decreased survival 5-year survival. estimated incidence 5.41 per 100,000 our target population Conclusions has been grossly underestimated context non-pigmented lesions are far more prevalent than previously thought. It known that worse outcomes. These not benefitting rapid access pigmented lesion clinics therefore outcome going.